European Teratology Society 
Monday 10th to Thursday 13th September 2018 in Berlin, Germany
Download the ETS Second Announcement
Dear Friends and Colleagues,
It is with great pleasure that I invite you to attend the 46th annual meeting of the European Teratology Society in Berlin, Germany 10th to 13th September 2018. The conference will take place in the conveniently located NH Alexanderplatz Hotel, in the centre of Berlin, within easy reach of the many cultural locations within this city.
The Key sessions for ETS 2018 will include:
Education Course
Adverse Outcome Pathway’s (AOP)
Symposia
- Infectious diseases during pregnancy
- Microbiome – during pregnancy and infancy
- Ocular Teratogens: New visions on old dangers
- Endocrine disruption: Focus on the Thyroid
- The programme will also include the ETS/TS debate on “Are we ready for alternative testing?”
- The ETS Presidents’ award lecture on Zika virus: an update
- The ETS/Elsevier best manuscript presentation
- Free communication and poster presentations will provide opportunity for all participants to present and discuss their activities.
In addition to the scientific programme which will provide a stimulating atmosphere for scientific exchanges as well as opportunity to make new acquaintances; there is Berlin: The conference hotel is in a peaceful corner of the city called Friedrichshain – Berlin’s hip, artists’ district. Just next door there is a park and open air cinema, and down the road, a handful of coffee shops and beer gardens. It is also located just three tram stops from Alexanderplatz square: which is one of the liveliest places in Berlin, with shops, cinemas, restaurants, and many other historical attractions within walking distance.
Finally, with resources in mind: in addition to the blocks of rooms reserved in the NH Alexanderplatz Hotel at preferential rates for the conference delegates, cheaper accommodation options are available in Berlin to meet all budgets.
I look forward to welcoming you and your colleagues to the ETS conference in 2018.
Welcome to Berlin,
Dr. Nicola Powles-Glover,
Vice President of the ETS.
ETS Officers
| President: | Shay Giles |
| Past President: | Alberto Mantovani |
| Vice-President: | Nicola Powles-Glover |
| Treasurer: | Steffen Schneider |
| Secretary: | Richard Bartlett |
ETS Council
| Deirdre Brennan | |
| Steven Van Cruchten | |
| Julian French | |
| Elise Lewis | |
| Francesca Maranghi | |
| Derek Newall | |
| Birgit Peter | |
| Richard Vogel | |
| Dirk Marien |
Meeting Organisation
Solution office e.K.
Julia Robker
Bergstr. 2
29646 Bispingen
Germany
Tel.: +49 5194 97449-0
Fax: +49 5194 97449-4
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Programme Overview
| Monday 10th September 2018 | |||
|---|---|---|---|
| ETS Council Meeting 1 | 09.00-13.00 | ||
| ETS Education Course: | 14.00-14.15 | Introduction on AOPs | Manon Beekhuijzen, Charles River, Den Bosch, The Netherlands |
| Adverse Outcome Pathways Chairs: Manon Beekhuijzen (The Netherlands), Alberto Mantovani (Italy) |
14.15-15.00 | Using AOP for the hazard characterization of pesticides | Susanne Hougaard, Danish Environmental Protection Agency, Denmark |
| 15.00-15.45 | Using AOPs fort he assessment of Endocrine Disruptors- like modes of action | Stefano Lorenzetti, National Institute of Health, Italy | |
| 15.45-16.15 | Coffee | ||
| 16.15-17.00 | Using AOP for safety assessment of pharmaceuticals | Jane Stewart, ApconiX Ltd., UK | |
| 17.30-18.30 | Young Scientists' Happy Hour | NH Hotel Berlin Alexanderplatz | |
| 18.30 | Welcome Reception | NH Hotel Berlin Alexanderplatz | |
| Tuesday 11th September 2018 | |||
| Welcome address | 09.00-09.15 | ETS President | |
| President’s Award Lecture | 09.15-10.00 | Zika virus: an update | David Baud, University Hospital, Lausanne, Switzerland |
| Symposium 1 | 10.00-11.00 | S1-1 Global health aspects of infections in pregnancy | Walter Ricciardi. National Institute of Health, Italy |
| 11.00-11.30 | Coffee | ||
| 11.30-12.15 | S1-2 Clinical aspects of infectious diseases during pregnancy | Manon Vouga, Lausanne University Hospital, Switzerland | |
| 12.15-12.30 | General Discussion with chairs ands speakers | ||
| 12:30-13.30 | Lunch | ||
| Symposium 2 | 13.30-14.15 | S2-1 ‘Eye’ spy: Emerging visions and new insights in ocular teratology | Deirdre Brennan, University College Dublin, Ireland |
| Ocular Teratogens: New visions on old dangers | 14.15-15.00 | S2-2 Opioids and the developing visual system | Alan Mulvihill, NHS Lothian Edinburgh, UK |
| Chairs: Deirdre Brennan (UK), Luc De Schaepdrijver (Belgium) | |||
| 15.00-15.30 | Coffee | ||
| 15.30-16.15 | S2-3 Ocular Gene Therapy for Inherited Retinal Blindness | Bart Leroy, Ghent University Hospital, Belgium | |
| Free communications Chairs: Dirk Mariën (Belgium), Geertje Lewin (Germany) |
16.15-16.30 | F1 The Association between the Maternal Diet and the Gut Microbiome: a Systematic Review | Siofra Maher, University College Dublin, Ireland |
| 16.30-16.45 | F2 Retrieving mode of action information by automated effect pattern analysis using the zebrafish embryo toxicity test | Elisabet Teixido, UFZ, Leipzig, Germany | |
| 16.45-17.00 | F3 Ontogeny of key zebrafish genes involved in the disposition of xenobiotics from the embryonic until the juvenile stage in the zebrafish embryo assay with metabolic activation | Chloé Bars, UAntwerp, Belgium | |
| 17.00-17.15 | F4 An integrative analysis through systems biology tools suggest beta-catenin protein (CTNNB1) interconnecting the main hypotheses of thalidomide teratogenesis | Thayne W Kowalski, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil | |
| Poster session | 17.20-19.00 | ||
| Wednesday 12th September 2018 | |||
| Symposium 3 Endocrine disruption: focus on the thyroid Chairs: Elise Lewis (US), Steffen Schneider (Germany) |
08.30-09.15 | S3-1 Thyroid hormones and the developing brain: Rodent models to define phenotypes, elucidate mechanisms, and inform quantitative predictive modeling | Mary E. Gilbert, US EPA, North Carolina, USA |
| 09.15-10.00 | S3-2 Thyroid hormone measurement in developmental toxicity studies: technical and interpretation issues | Volker Strauss, BASF SE, Ludwigshafen, Germany | |
| 10.00-10.30 | Coffee | ||
| 10.30-11.15 | S3-3 Disruption of thyroid physiology during pregnancy: a vulnerable timeframe | Tim Korevaar, Erasmus UMC, Rotterdam, The Netherlands | |
| Free communications Chairs: Shay Giles( Ireland), Derek Newall (UK) |
11.15-11.30 | F5 An AOP-based Ontology for Spina Bifida Caused by Disturbance in Retinoic Acid Signaling | Aldert Piersma, RIVM, Bilthoven, The Netherlands |
| 11.30-11.45 | F6 An adverse outcome pathway framework to support the assessment of DART liabilities of compounds. | Alun Myden, Lhasa Limited, Leeds, UK | |
| 11.45-12.00 | F7 Aberrant Methylation of Pax3 Gene and Neural Tube Defects in Association with Exposure to Polycyclic Aromatic Hydrocarbons | Aiguo Ren, Peking University, Beijing, China | |
| 12.00-12.15 | F8 Concentration-response analysis of data obtained in mouse foetuses exposed in utero at E8 to azole antifungals (cyproconazole and triadimefon) alone or in mixture. | Elena Menegola, Univeristà degli Studi di Milano, Milan, Italy | |
| 12.15-13.30 | Lunch | ||
| Young Scientists Round Table (including lunch) Chairs: Deirdre Brennan (Ireland), Steven Van Cruchten (Belgium) |
12.30-12.40 | Introduction by Chairs | |
| 12.40-12.50 | Identifying latent sources of exposure to mercury in the mediteranean: the case of Cyprus | Ismini Tzanaki, European University of Cyprus, Nicosia, Cyprus | |
| 12.50-13.00 | Necessity of screening for volatile air pollutants in industrial workers: potential health implications | Athanasios Athanasiou, European University of Cyprus, Nicosia, Cyprus | |
| 13.00-13.10 | Effects of Octylphenol and Bisphenol A on calcium signaling in cardiomyocyte differentiation from mouse embryonic stem cells | Jae-Hwan Lee, Chunbuk National University, Chunbuk, Republic of Korea | |
| 13.10-13.20 | Preterm piglets as a translational model for premature babies: focus on hepatic drug metabolism | Laura Buyssens, UAntwerp, Belgium | |
| 13.20-13.30 | Discussion and Conclusion | ||
| ETS/TS Exchange Discussion Chairs: Paul Barrow (Switzerland), Sue Makris (USA) |
13.30-14.15 | Are we ready for alternative testing? | Discussants: Manon Beekhuijzen, Charles River, ’s-Hertogenbosch, The Netherlands. Nicole Kleinstreuer, NIH, Durham, USA |
| Symposium 4 Young Scientists Symposium Chairs: Deirdre Brennan (Ireland), Dirk Mariën (Belgium) |
14.15-14.50 | S4-1 Localization of cytochrome P450 activity in the zebrafish and larva | Evy Verbueken, UAntwerp, Belgium |
| 14.50-15.25 | S4-2 Optimization of drug metabolism in the metabolic zebrafish developmental toxicity Assay (mZEDTA) | Casper Pype, UAntwerp, Belgium | |
| 15.25-15.55 | Coffee | ||
| 15.55-16.30 | S4-3 Applying discovery toxicology approaches for prediction of developmental phenotypes | Kathryn Wolton, Syngenta, Bracknell, UK | |
| 2019 ETS Conference Presentation | 16.30-16.45 | Presentation on the 2019 ETS conference in Cologne Germany | Steven Van Cruchten, Belgium |
| ETS AGM | 16.45-18.00 | ETS members only | |
| ETS Gala Dinner | 19.30- | Umspannwerk Ost | |
| Thursday 13th September 2018 | |||
| Elsevier Award Lecture | 09.00-09.45 | Intra-laboratory validated human cell-based in vitro vasculogenesis/angiogenesis test with serum-free medium biomarkers of human neurodevelopmental toxicity | Tarja Toimela, University of Tampere, Tampere, Finland |
| Symposium 5 Microbiome during pregnancy and infancy Chairs: Birgit Peter (The Netherlands), Nina Hallmark (France) |
09.45-10.30 | S5-1 The Microbiome and Early Development: An Introduction | Tim Gant, Public Health England, UK |
| 10.30-11.00 | Coffee | ||
| 11.00-11.45 | S5-2 The Microbiome and Pregnancy | Omry Koren, Bar-Ilan University, Israel | |
| 11.45-12.30 | S5-3 The Microbiome and Brain Development | Rochellys Diaz Heijtz, Karolinska Institute, Sweden | |
| Farewell Address | 12.30-12.40 | ||
| ETS Council Meeting 2 | 13.00-14.00 | ||
| 9th Berlin Workshop on Developmental Toxicology Click here for more information |
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Call for Abstracts
Participants interested in giving an oral or poster presentation are invited to submit an abstract. Work on topics related to the main symposia or the education course and ETS/TS Discussion, will be given preference for free communications.
Submitted abstracts will be reviewed by the ETS officers or selected experts. Accepted abstracts received before 30th April 2018 will be published in the Special Conference Issue of Reproductive Toxicology. Abstracts received after this date will be distributed at the meeting.
Abstract template:
The maximum size of posters is 1000 mm wide x 1500 mm high (i.e. portrait format).
- Authors names should appear in bold, with surname first followed by full first name and second initial. Presenting author should be indicated with an asterisk after surname. Example: Beekhuijzen*1 Manon, Mantovani2 Alberto, Barrow3 Paul. Failure to follow this format will result in incorrect indexing in the journal.
- Affiliation in italics, name of institute, place and country only. Multiple affiliations indicated by superscript numbers after surnames.
- One line spacing before body text.
- Abstract body in plain text in one paragraph, no indents or empty lines. No figures or tables
- Up to three references may be cited indicated by numbers in square brackets in line with the text. The reference style of Reproductive Toxicology should be used (https://www.elsevier.com/journals/reproductive-toxicology/0890-6238/guide-for authors#20300).
- Organize text in: introduction, methods, results and conclusions. Provide factual text. Avoid general statements like: “results will be presented”.
- Use 300 up to a maximum of 500 words for complete abstract (including title, authors, affiliation and text).
- Add preference choice for poster or oral presentation.
Abstract deadline (extended): 30th April 2018
Please email abstracts to: This email address is being protected from spambots. You need JavaScript enabled to view it.
ETS/Elsevier Prizes
The following prizes will be awarded during the ETS meeting:
- The Teddy Edwards Prize for Research into Congenital Malformations, awarded to the poster or free communication, which best exemplifies the aims of the Society.
- The ETS and Elsevier Publication Award Prize for best Reproductive Toxicology manuscript in the previous year.
- The ETS Prize given best poster or free communication delivered by a young scientist at the conference.
- The Elsevier Best Presentation Award for best poster or free communication at the conference.
- The ETS Presidents Award lecture, given by an esteemed member of the society at the invitation of the president.
- The ETS Young Scientist Round Table Medal for the best presentation at the young scientist round table discussion session.
ETS Young Scientist/Student Support
Thanks to our Sustaining Membership Sponsors, the ETS has the opportunity to encourage, educate and support a number of young scientists/students through travel grants, research/congress bursaries, young scientist prizes and reduced registration fees. In order to be eligible, students must submit an abstract for presentation at the conference and apply for membership to the Society. Applications should be made by the student’s Supervisor to the Secretary of the ETS. Awards will be given at the discretion of the ETS.
ETS Secretary: This email address is being protected from spambots. You need JavaScript enabled to view it.
Education Course: Adverse Outcome Pathways
More information coming soon
Social Programme
Welcome Reception – 10th September 2018, 18.30 h
The Welcome Reception will take place at the conference venue, the NH Hotel Berlin
Alexanderplatz.
We would like to invite you to this get-together to meet with old and new colleagues and friends and have a good and merry start to the Conference. Even late-comers will have a chance to come around and enjoy the evening.
Young Scientists Happy Hour
The Young Scientists Happy Hour, an informal get-together to foster networking opportunities for students, researchers and professionals of all ages will take place on Monday 10th September 2018 at the same venue where the Welcome Reception takes place.
ETS Conference Dinner – 12th September 2018, 19.30 h
The conference dinner will take place in the restaurant Umspannwerk Ost also located in Friedrichshain like the conference hotel.
The listed building is the oldest transformer station in Berlin and was built in 1899 to 1900 from the architect O. Springmann as a transformation station for steady supply of electricity in Berlin.
The building has style elements of Renaissance. The mighty steel-glas gates in the ground floor are today the entrance of the 7 meter high restaurant with an open kitchen. The gallery of the restaurant was former the integrated gangway where the transformation process was operated and controlled.
Dress code: Business casual
| Address: | Umspannwerk Ost Palisadenstraße 48 10243 Berlin Germany |
ETS Annual Meeting Registration
Please register online at: http://www.etsoc.com you will be able to pay directly by credit card (American Express, Master Card and Visa).
The fees quoted are inclusive of VAT (19%). A VAT receipt will be issued to permit VAT registered companies to reclaim the tax.
Registration Fees
Complete Congress (including 19% VAT)
| Until 31 May 2018 | 01 - 30 June 2018 | After 30 June 2018 | |
|---|---|---|---|
| ETS Members | € 445.00 | € 475.00 | € 565.00 |
| Non-Members | € 540.00 | € 570.00 | € 660.00 |
| Students* | € 130.00 | € 140.00 | € 165.00 |
Above fees include all scientific sessions, free communications, lunch, welcome reception and ETS Conference dinner.
One-Day Registration (including 19% VAT)
| Until 31 May 2018 | 01 - 30 June 2018 | After 30 June 2018 | |
|---|---|---|---|
| ETS Members | € 130.00 | € 140.00 | € 160.00 |
| Non-Members | € 165.00 | € 175.00 | € 215.00 |
| Students* | € 65.00 | € 70.00 | € 75.00 |
One-Day fees include the ETS lectures, free communications and lunch for the registered day.
Education Course (including 19% VAT)
| Until 31 May 2018 | 01 - 30 June 2018 | After 30 June 2018 | |
|---|---|---|---|
| ETS Members | € 90.00 | € 100.00 | € 135.00 |
| Non-Members | € 130.00 | € 145.00 | € 170.00 |
| Students* | € 50.00 | € 60.00 | € 75.00 |
Accompanying Person (including 19% VAT)
| Until 30 June 2018 | After 30 June 2018 | |
|---|---|---|
| € 100.00 | € 100.00 |
The Accompanying Person fee includes welcome reception and ETS Conference dinner. Entrance to the scientific sessions and lunch is not included.
* Students registration to be supported by supervisors’ letter.
Cancellation and Refund Policy
Cancellations are to be notified in writing to the ETS Conference Organizing office. Refunds will be made under the following conditions:
- You may cancel at no penalty within 48 hours of placing your registration.
- Until 1 July 2018 a 60% refund of the registration fee will be given.
- After 1 July 2018, no registration fees will be refunded.
- All refunds will be handled after the Conference.
Accommodation
The conference hotel is holding a limited number of rooms until the 30th July.
The congress hotel (Hotel NH Berlin Alexanderplatz) is located close to the Alexanderplatz where are many hotels in different categories. Public transportation is very close to the hotel and gives the possibility to reach all cultural highlights easily.
Make your reservation as early as possible. Berlin is well booked all year!
| Hotel | Category | Distance to congress venue | Room | Price/ night * | rooms blocked | Available till | contact/ how to book |
|---|---|---|---|---|---|---|---|
|
NH Berlin Alexanderplatz |
congress venue | Classic single |
€ 109.00 |
70 | 30th July 2018 |
via telephone: +49 30 22385889 |
|
|
InterCityHotel Berlin Ostbahnhof |
2 km | Classic single |
€ 95.00 |
20 | 12th August 2018 |
via telephone: +49 30 29368300 |
|
|
Ibis Hotel Berlin Ostbahnhof |
2 km | Classic single |
€ 100.00 |
30 | 12th August 2018 |
via telephone: +49 30 257600 |
There are a lot of smaller hotels and bed and breakfasts in walking distance to the congress venue that can’t offer speacial allotments for conferences. It might be cheaper to have a look for a room in such a hotel. So delegates are welcome to book their own accommodation other than the accommodation service offered by the Congress Secretariat. You can have a look here (google maps).
Problems with your reservation?
If you should have problems with your hotel reservation, please contact Julia Robker, This email address is being protected from spambots. You need JavaScript enabled to view it..
ATTENTION: Avoid Hotel Fraud
Unfortunately, several exhibitors and attendees of different congresses each year fall prey to accommodation offers from fraudulent companies.
Fraudulent companies repeatedly email our show participants with room offers for the week of ETS. Their website and/or emails mention ETS Congress, and even include our logo in the hopes of looking like an official or legitimate provider.
These groups promote attractive deals with local accommodation providers, but once payment has been received, the company disappears and can no longer be contacted by phone or email. Once the attendee contacts the hotel directly about their room, they realise the hotel has no record of them or their stay. Not only is their money gone, they must then scramble to find last-minute accommodation, which is rarely convenient to the venue.
This practice takes money directly from our customers and negatively impacts their ETS experience. We do everything we can to stop these companies preying on our attendees, and we don’t want this to happen to you.
Room reservations should be made directly with the hotel, using the reservation method indicated in their listing below. This is the only official way to book a room for Congress. Neither the ETS, nor solution office, utilize the services of any housing/accommodation vendor(s) and do not contact attendees regarding accommodations. Please do not make arrangements with any vendors who contact you directly to offer help with booking accommodations for the ETS Congress 2018.
Meeting Organisation – Registration Queries
Solution office e.K.
Julia Robker
Bergstr. 2
29646 Bispingen
Germany
Tel.: +49 5194 97449-0
Fax: +49 5194 97449-4
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Congress Venue
Hotel NH Berlin Alexanderplatz
Landsberger Allee 26-32
10249 Berlin
Germany
https://www.nh-hotels.com/hotel/nh-berlin-alexanderplatz
The NH Berlin Alexanderplatz is located near the famous Alexanderplatz in Friedrichshain, a little bit East of the city center. Over the road there is the ‘’Volkspark Friedrichshain“, a park with two lakes. Friedrichshain is one of the trendy districts of Berlin and has experienced gentrification. Close to the hotel is a tram and a bus station.
- 0.25 km Volkspark Friedrichshain
- 0.39 km Berliner Kriminaltheater
- 4.52 km Rotes Rathaus
- 0.56 km Computerspielmuseum
Climate in Berlin
September is still a good month to travel to Berlin. By day it could get up to 20 degrees. At night temperatures fall to about 9 degrees. So it is better to take a jacket with you.
How to get to Berlin
You can get to Berlin easily by plane or by train.
By plane
Berlin has two airports, Berlin Schönefeld (SXF) and Berlin Tegel (TXL). The new airport BER will not open before 2020.
By train
Information coming soon
From the airport to the hotel
Hotel Address:
Hotel NH Berlin Alexanderplatz
Landsberger Allee 26–32, 10249 Berlin, Germany
Phone: +49 30 4226130
By Bus / Metro
From the Airport Tegel (TXL): Take the bus TXL, which departs every 5–10 minutes, to
get to the station “Alexanderplatz”. From there take the M5 or the M6 for the station
“Klinikum im Friedrichshain”. It’s a 40–50 minutes trip from the airport Tegel.
From the Airport Schönefeld (SXF): Take the S9, which departs every 10–15 minutes,
for the station “Alexanderplatz”. Please switch trains and take the M5 or the M6 for the
station “Klinikum im Friedrichshain”. It’s a 50 minutes trip from the airport Schönefeld.
Taxi
From Tegel: it will take 40 minutes and cost around 35–40 €.
From Schönefeld: it will take 40 minutes and cost around 40–50 €.
By Train
From Klinikum im Friedrichshain: Turn right and you will find the hotel on the opposite street.
Closest metro station: Klinikum im Friedrichshain
You can choose between a single ticket (3,40 €), a day ticket (7,70 €) or a ticket for a week (37,50 €). Within the ticket price, you can take the train and the bus in all sectors (ABC).
By car
The hotel’s GPS Coordinates: 52.523316°N 13.436977°E
Parking: Offsite: 2 €/hour, 15 €/day
Please contact Julia Robker, This email address is being protected from spambots. You need JavaScript enabled to view it. for more information.
Language
The official language in Germany is German. It is a West Germanic language. German is also spoken in parts of neighbouring countries like Austria, Switzerland, Luxemburg, Belgium and Lichtenstein.
Currency & Exchange
As Germany is a member of the European Union the currency is the Euro (€), divided into 100 Cent. Currency can be exchanged at the airport, banks and exchange offices. ATMs are widely available.
Electricity
The electrical supply in Germany is 230v/50Hz. Sockets are suitable for europlugs and plugs of Type F (grounding clips on both sides).
Check that your appliance supports dual voltage and frequency.
Visas
Germany is a member of the European Union and of the Schengen Area.
Therefore, separate immigration controls are maintained. Citizens of EU and EEA countries (and Switzerland) only require a valid national identity card or passport.
Non-EU nationals may need to apply for a visa to travel to Berlin. Please consult the following link: www.auswaertiges-amt.de/en/einreiseundaufenthalt/visabestimmungen-node
Visa Requirements
It is the sole responsibility of the attendee to take care of his / her visa requirements. Attendees who require an entry visa must allow sufficient time for the application procedure. Attendees should contact the nearest embassy or consulate to determine the appropriate timing of their visa applications. It is recommended to apply for a visa at least 3 months in advance of the Congress. When the registration has already been paid, the registration fee minus a handling fee of € 50.00 will be refunded after the Congress if the visa was applied for in time, and proof of this, together with an official notice from the embassy confirming that a visa could not be granted, is forwarded to: This email address is being protected from spambots. You need JavaScript enabled to view it.
Letter of invitation
If you need a letter of invitation for your visa you can request one via: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Please note that a letter of invitation will only be issued after you have registered and paid for the congress.
Sponsors & Exhibitors
There are several opportunities to sponsor the ETS annual meeting. Please have a look at the application form or contact the meeting organisation directly under: This email address is being protected from spambots. You need JavaScript enabled to view it.
Download Application for Sponsorship
