Published: 12 December 2019
Category: Annual ETS Meetings
Annual ETS Meetings

Monday 20th to Thursday 23rd September 2021 in Madrid, Spain

Due to the current COVID-19 Situation 2020s ETS meeting will be hold as a one-day virtual meeting with a keynote lecture, one symposium, and some flash talks. An ETS/BDRP debate will also be part of our virtual programme. Click here for more information and registration (available August 5th 2020).

Our meeting in Madrid (Spain) has been postponed until September 20th to 23rd 2021. We hope to see you all there!

Thank you very much for your patience and for supporting our society,

Arantza Muriana, organizer of the 2020 ETS meeting




Dear Friends and Colleagues,

With great pleasure, I would like to invite you all to the 48th Annual Meeting of the European Teratology Society (ETS). The conference will be held from Monday 20th to Thursday 23rd of September 2021 in Madrid, the third-largest city in the European Union which monocentric metropolitan area is the third-largest in the EU too.

The key sessions for ETS 2021 will include:

Educational course on Reproductive system


  • Symposium 1: Growth retardation. Clinical outcomes
  • Symposium 2: Neurobehavioral effects on Development
  • Symposium 3: Nanoparticles and development
  • Symposium 4: Regulatory challenges in DART data interpretation

The programme will also include:

  • The Round table on “Endocrine disruption (sexual and thyroid, policy/ approach to population influences)”.
  • The Presidents’ Award Lecture.
  • The ETS/TS Exchange Lecture.
  • The Elsevier Award Lecture with the best manuscript presented.
  • Free presentations and Posters presentations, that will provide opportunity for all participants to present and discuss their activities.

In addition to the scientific programme, which will provide a stimulating atmosphere for scientific exchanges as well as opportunity to make new acquaintances, there is Madrid. The Rafael Hoteles Atocha is located in the Atocha neighborhood, a prime location due to its proximity to the station which has connections to main Spanish cities, but also because of how close it is to the most significant cultural area of the city: the “Golden Triangle of Art”, which includes the Reina Sofia National Museum Art Centre, the Prado Museum and the Thyssen Bornemisza Museum. The hotels’ great location in this neuralgic centre of Madrid will allow you not only visiting the famous art museums of the city, but also walking around one of the biggest green lung of Madrid, Parque del Retiro, and enjoying Spain‘s legendary nightlife and Madrid’s tapas culture, that will make your mouth water during your walking through the city with the tempting food and drink offered in the Spanish capital. Accommodation options will be available to meet all budgets, even the Rafael Hoteles Atocha will hold the Conference, including the reception in its relaxing garden.

We keep encouraging you to actively participate in and strengthen this scientific programme by submitting your abstract for an oral presentation or poster by the 30 April 2020 to This email address is being protected from spambots. You need JavaScript enabled to view it.. Best submitted works will be acknowledged by several awards. Also consider submitting a manuscript (original research, review or position paper) for the Special Issue of the 48th ETS meeting in Reproductive Toxicology. Submission should be done via and selecting SI: ETS2020 by the 30 April 2020.

I look forward to welcoming you and your colleagues to the ETS conference in 2020. Welcome to Madrid!

Arantza Muriana Miralles
On behalf of the entire ETS Council


ETS Officers

President: Nicola Powles-Glover
Vice-President: Steven Van Cruchten
Treasurer: Steffen Schneider
Secretary: Stephanie Clubb

ETS Council

Arantza Muriana
Elena Menegola
Alan Hoberman
Elise Lewis
Kathryn Wolton
Emily Richmond
Jason Manton
Kirsten Van Dycke
Dirk Marien

Meeting Organisation

Solution office e.K.

Pia Schröder
Bergstr. 2
29646 Bispingen

Tel.: +49 5194 97449-0
Fax: +49 5194 97449-4
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Preliminary Programme Overview

Monday 14th September 2019
ETS Council Meeting 1 09.00-13.00    
ETS Education Course:
Fetal Pathology
Chairs: Graham Bailey (Belgium), Julian French (UK)
14.00-14.10 Introduction Graham Bailey, Janssen R&D, Belgium
14.10-14.50 External and Visceral examination Julian French, Syngenty Ltd, UK
14.50-15.30 Skeletal examination Ruth Clark, UK
15.30-15.40 First seesion - Discussion and questions  
15.40-16.10 Coffee  
16.10-16.40 Application of micro-CT to fetal examination Arun Tatiparthi, Covance, USA
16.40-17.20 Interpretation of fetal pathology results and other techniques used Graham Bailey, Janssen Pharmaceutica, Belgium
17.20-17.30 Second session - Discussion and questions  
Young Scientists' Happy Hour 17.30-18.30   Maternushaus
Welcome Reception togehter with ESTP

18.30   Maternushaus
Wednesday 18th September 2019  
Welcome address 09.00-09.10   ETS President - ESTP President

Symposium 1
Joint Symposium ETS-ESTP
Digital Pathology and Developmental Toxicology
Chairs: SteffenSchneider (Germany), Sibylle Groters (Germany)

09.10-09.50 S1-1 Towards a mechanistic approach in toxicology – using AOP´s in developmental toxicity assessment Aldert Piersma, RIVM, The Netherlands
09.50-10.30 S1-2 Status and prospect of the virtual embryo program Tom Knudsen, US EPA, USA
10.30-11.00 Coffee  
11.00-11.45 S1-3 The use of micro-CT imaging to examine and illustrate fetal skeletal abnormalities in rabbits and to prove concordance with Alizarin Red stained skeletal examination. Howard M. Solomon, GSK, UK
11.45-12.30 S1-4 Detection of ovarian follicles by deep learning Heike Marxfeld, BASF SE, Germany
12:45-13.45 Lunch  
13.30-14.10 S1-5 Optical coherence tomography to image cells and tissues 3D Jürgen Schnekenburger, University of Münster, Germany
Free communications
Chairs: Elena Menegola (Italy), Arantza Muriana (Spain)
14.15-14.30 F1 Do allogeneic murine pregnancy models predict the developmental liabilities of immune-stimulating antibodies? Kary Thompson, BMS, USA
14.30-14.45 F2 Assessing the placental transfer and exposure of TNF inhibitors in women with autoimmune diseases in vivo and via an ex vivo placenta perfusion approach Gaby Eliesen, Radboud UMC, The Netherlands
14.45-15.00 F3 Added value of plasma metabolite profiling in prenatal rat routine studies Jana Keller, BASF SE, Germany
15.00-.15.15 F4 The ontogeny of hepatic CYP450 protein abundance in the developing Göttingen Minipig: a new step towards a juvenile PBPK model Laura Buyssens, UAntwerp, Belgium
15.15-15.45 Coffee  
15.45-16.00 F5 Concordance between in vitro developmental toxicity assays and in vivo embryo-fetal development findings: the IQ DruSafe Assessment Mary Ellen McNerney, BMS, USA
16.00-16.15 F6 Validation of a novel human stem cell-based gene Expression assay for in vitro DART assessment Peter Racz, Toxys BV, The Netherlands
16.15-16.30 F7 Development of a database and in silico models for the early prediction of reproductive toxicity liabilities Paul Desert, Sanofi Pasteur, France
16.30-16.45 F8 Modeling craniofacial abnormalities in the developing zebrafish: implementation of new functional endpoints, determination of windows of susceptibility and evaluation of misoprostol as model compound Marta Barenys, University of Barcelona, Spain
16.45-17.00 F9 Teratogenicity susceptibility and cardiovascular system malformations: molecular analyses of HAND2 gene in thalidomide survivors Bruna Rengel, Federal University of Rio Grande do Sul, Brazil
Poster session

Thursday 19th September 2019  
President’s Award Lecture 09.00-09.45 Title TBD Jochen Buschmann, Germany
Symposium 2
Assisted Reproductive Technologies and pregnancy outcome
Chairs: Steven Van Cruchten (Belgium), Nicola Powles-Glover (UK)  
09.45-10.30 S2-1 The implementation of single embryo transfer: the biggest step towards a better outcome of children after ART Diane De Neubourg, Antwerp University Hospital, Belgium
10.30-11.00 Coffee  
11.00-11.45 S2-2 The health of children after ART Anja Pinborg, Rigshospitalet, Denmark
11.45-12.30 S2-3 Factors in ART impacting postnatal outcome John Dumoulin, Maastricht UMC, The Netherlands
  12:30-13.30  Lunch  
Young Scientists Round Table (including lunch)
Chairs: Deirdre Brennan (Ireland), Steven Van Cruchten (Belgium) 
12.30-13.30  Introduction by chairs  
12.40-12-50 Teratogenicity in mammals predicted by a non-mammalian test system, the zebrafish (Danio rerio) embryo Katharina Brotzmann, University of Heidelberg, Germany
12.50-13.00 The retinoic acid pathway as a source of gene expression biomarkers of developmental toxicity in the zebrafish embryotoxicity assay Laura Samrani, RIVM, The Netherlands
13.00-13.10 Asb2 bèta is essential for embryonic cardiomyocyte development and filamin B degradation in epicardium and endocardium in mice Seul Gi Park, Chungbuk National University, Republic of Korea
13.10-12.20 Poland syndrome complicated with metabolic syndrome and gynecomastia Ismini Tzanaki, European University Cyprus, Cyprus
13.20-13.30 Discussion and Conclusion  
ETS/TS Exchange Discussion
Chairs: Manon Beekhuijzen (The Netherlands), Sue Makris (USA)
13.30-14.15  The new 3Rs: Reproducibility and Rigor in Reproduction studies Shay Giles, UCD, Ireland and Don Stump, Charles River, USA
Free communications
Chairs: Stephanie Clubb (UK), Manon Beekhuijzen (The Netherlands)
14.15-14.30 F10 Allocation of pesticide active substances to cumulative risk groups for effects on reproduction and development Mary Moxon, UK 
14.30-14.45 F11 Do PFOS/PFOA levels in Italian women pose a risk to fetal growth Alberto Mantovani, Instituto Superiore di Sanita, Italy
14.45-15.00 F12 Non-neurotoxic concentrations of single environmental chemicals become neurotoxic in mixture: developmental neurotoxicity (DNT) evaluation using human in vitro model Anna Bal-Price, JRC, Italy
15.00-15.15 F13 Reproductive and Pathology Assessment of Bisphenol AF Vicki Sutherland, NTP, USA
  15.30-16.00 Coffee  
  16.00-16.30 Update Task Forces (Folic Acid completed, Thyroid, Zebrafish, Artificial Intelligence)  
2020 ETS Conference Presentation 16.30-16.45 Presentation on the 2020 ETS conference  
ETS AGM 16.45-18.00   ETS members only
ETS Gala Dinner

19.30-   Wartesaal am Dom
Friday 20th September 2019  
Elsevier Award Lecture 09.00-09.45 Species-specific developmental toxicity in rats and rabbits: Generation of a reference compound list for development of alternative testing approaches Elisabet Teixidó, Barcelona, Spain
Symposium 3
Updated regulatory guidances on reproductive testing of pharmaceuticals and chemicals
Chairs: Jason Manton (UK), Stephanie Clubb (UK)
09.45-10.30 S3-1 Recent Updates on Regulatory Guidance for Reproductive Testing of Pharmaceuticals - ICH S5(R3) Paul Barrow, F. Hoffmann-La Roche, Basel, Switzerland
10.30-11.00 Coffee  
11.00-11.45 S3-2 Recent Updates on Regulatory Guidance for Developmental Toxicity Testing of Chemicals - OECD 414 Manon Beekhuijzen, Charles River Laboratories, s-Hertsogenbosch, The Netherlands
11.45-12.30 S3-3 New Guidance on EDC’s in the EU (EFSA/ECHA Guidance; OECD GD 150) for Agrochemicals and Biocides Emily Richmond, Exponent, Harrogate, United Kingdom
Farewell Address 12.30-12.40    
ETS Council Meeting 2 13.00-14.00    
Monday 20th Tuesday 21st Wednesday 22nd Thursday 23rd
ETS Council Meeting 1
President’s Award Lecture
Symposium 1
Growth Retardation
Symposium 3
Nanoparticles and development
free communications
Elsevier Award Lecture
Symposium 4
Regulatory challenges
YS Round Table
Endocrine Disruption Round Table
2nd council meeting
Education course and welcome reception
YS Happy Hour
Symposium 2
YS free communications
poster session
ETS/TS debate
free communications
AGM and Gala dinner

Call for Abstracts

Participants interested in giving an oral or poster presentation are invited to submit an abstract. Work on topics related to the main symposia or the education course and ETS/ TS Discussion, will be given preference for free communications. Submitted abstracts will be reviewed by the ETS officers. Accepted abstracts received until 1st April 2020 will be published in the Special Conference Issue of Reproductive Toxicology. Abstracts received after this date will be distributed at the meeting.

Abstract template (Times New Roman 12):

  • Title in bold
  • Authors names should appear in bold, with surname first followed by full first name and second initial. Presenting author should be indicated with an asterisk after surname. Example: Beekhuijzen*1 Manon, Mantovani2 Alberto, Barrow3 Paul.
    Failure to follow this format will result in incorrect indexing in the journal.
  • Affiliation in italics, name of institute, place and country only. Multiple affiliations indicated by superscript numbers after surnames.
  • One line spacing before body text.
  • Abstract body in plain text in one paragraph, no indents or empty lines. No figures or Tables
  • Up to three references may be cited indicated by numbers in square brackets in line with the text. The reference style of Reproductive Toxicology should be used (
  • Organize text in: introduction, methods, results and conclusions. Provide factual text. Avoid general statements like: “results will be presented”.
  • Use 300 up to a maximum of 500 words for complete abstract (including title, authors, affiliation and text).
  • Add preference choice for poster or oral presentation.

Abstract deadline is not available yet.

ETS/Elsevier Prizes

The following prizes will be awarded during the ETS meeting:

  • The ETS and Elsevier Publication Award for best Reproductive Toxicology manuscript in the previous year.
  • The ETS Prize given best poster or free communication delivered by a young scientist at the conference.
  • The Elsevier Best Presentation Award for best poster or free communication at the conference.
  • The ETS Presidents’ Award lecture, given by an esteemed member of the ETS at the invitation of the president.
  • The ETS Young Scientist Round Table Medal for the best presentation at the young scientist round table discussion session.

ETS Young Scientist/Student Support

Thanks to our Sustaining Membership Sponsors, the ETS has the opportunity to encourage, educate and support a number of young scientists/students through travel grants, research/congress bursaries, young scientist prizes and reduced registration fees. In order to be eligible, students must submit an abstract for presentation at the conference and apply for membership to the Society. Applications should be made by the student’s Supervisor to the Secretary of the ETS. Awards will be given at the discretion of the ETS.

ETS Secretary: This email address is being protected from spambots. You need JavaScript enabled to view it.

Social Programme

Welcome Reception – Monday 14th September – Rafaelhoteles Atocha

(Méndez Alvaro, 30 – 28045 Madrid)

On the evening of Monday 14th September we would like to invite you to join us at the Welcome Reception.

The Reception will take place in the congress venue where you will have the opportunity to meet colleagues and friends, to chat and prepare yourself for the following days of the conference.

The Reception will last about 2 hours, with drinks and light snacks. There are several restaurants in walking distance to the venue to go out for dinner afterwards.

Join us, have a drink and enjoy the evening.

ETS Conference Dinner – Wednesday 16th September – Casa Suecia

(Calle del Marqués de Casa Riera 4, 28014 Madrid)

The conference dinner will take place in the restaurant “Casa Suecia“ which has a beautiful rooftop terrace with great views over the city of Madrid. You are invited to enjoy a delicious dinner made of typical Spanish tapas and to meet friends and colleagues in a relaxed atmosphere. This year dinner will be focused on networking and communication. With the stunning bar Hemingway for an after-dinner party.

The restaurant is only 25 minutes’ walking distance to the congress venue and has also a direct metro connection.

Please note that the dinner is no longer included in the registration fee. So please add the congress dinner to your registration to enjoy this evening with us and take the opportunity to spend a great evening above the city roofs of Madrid.

ETS Annual Meeting Registration

Registration details are not available yet.

Register now

Register now


The congress hotel (Rafaelhoteles Atocha) is located in the district Atocha, close to one of the two main stations (AVE Madrid Puerta de Atocha station). It is close to the most significant cultural area in the city: the “Golden Triangle of Art”, which includes the Reina Sofia National Museum Art Centre, the Prado Museum and the Thyssen Bornemisza Museum.

All over Madrid you can find hotels and hostels in different categories. Make your reservation as early as possible. Madrid is well-booked all year!

Here are a few hotels which provide a limited contingent of rooms (slide left and right if you think the table has been cut off):

Hotel Category Distance to congress venue Room Price / night incl. breakfast Rooms blocked 16–20 Sept. 2019 Available till Contact / how to book

Rafaelhoteles Atocha

**** - Standard double room, for double or single use € 165,00 for single use € 178,20 for double use 50 20th August 2020 www.rafaelhoteles. com/en/ets-2020. html
IBIS Budget Madrid Centro Lavapiés * 1,5 km Standard double bed room, for double or single use € 90,00 for single use € 95,00 for double use
Minimum length of stay: 3 nights
The hotel will charge a 20% nonrefundable fee at time of the booking. The balance will be charged at the same credit card 15 days before the arrival.
30 4th September 2020 via e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Credit Card Guarantee

In order to guarantee accommodation, you need to provide your credit card details to the hotel.

Payment Options

Accommodation must be paid directly to the hotel during your stay.

Change your reservation

If you need to change your reservation, please contact the hotel directly.

Meeting Organisation – Registration Queries

Solution office e.K.

Pia Schröder
Bergstr. 2
29646 Bispingen

Tel.: +49 5194 97449-0
Fax: +49 5194 97449-4
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Congress Venue

Rafaelhoteles Atocha

Méndez Alvaro, 30
28045 Madrid, Spain

Tel: +34 914 688 100
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

The congress hotel (Rafaelhoteles Atocha) is located in the district Atocha, close to one of the two main stations (AVE Madrid Puerta de Atocha station). It is close to the most significant cultural area in the city: the “Golden Triangle of Art”, which includes the Reina Sofia National Museum Art Centre, the Prado Museum and the Thyssen Bornemisza Museum.

Also close is the district Lavapiés, the most multicultural district of Madrid, with many bars and restaurants. About half of its residents originate from Africa, Asia or Latin America. Plenty of world music bars and many alternative theaters and art galleries, as well as Indian restaurants, alternative cafés, African music and South American shops.


Madrid has a continental climate, hot and dry in summer and cold in winter with frequent frosts during the night and the occasional snowfall. September generally has very pleasant temperatures. The average maximum daytime temperature lies around 25°C (77°F). Spring and autumn are mild and the best time to visit Madrid. So, what to wear in September? For warm to hot days, as are common for the month, pack lightweight everything: short-sleeved tees and shirts, lightweight pants or shorts, and capri pants for women. For men, think in terms of dressy shorts and polos or button-downs. Jeans and other long pants might feel a bit too warm in the daytime, but would be a good addition for evenings after the sun goes down and things begin to cool off. You also might need a lightweight jacket or sweater for nights out.


By air

The Madrid Barajas International Airport is located 13 km north-east of the city. All commercial flights into Madrid use this airport.
From the airport you can take the metro line 8 until the last stop at Nuevos Ministerios. From there you take the metro line 6 until the station Méndez Álvaro. From here it is a walk of about 1 km to the conference hotel.
You can also take the bus, line Exprés-203, until the station Atocha Renfe. From there it is ca. 1 km to the conference hotel.
You can find information on the website of the airport (https://www.aeropuertomadridbarajas. com/eng/).
If you want to take a taxi, it will take about 30 minutes, depending on the traffic.

By train

There are two main stations in Madrid: Atocha (close to the congress venue) and Chamartín. The extensive Renfe railway network has its capital in Madrid, where trains from all over Spain arriving. Also international trains from France and Portugal arrive and depart in Madrid. Under you can search for train connections.

Get around

You can find detailed information about the public transport on the official tourism website under
If you want to travel around in Madrid, the Tourist Travel Pass is a cheap and practical way. It allows unlimited trips in all types of public transport within the chosen timeframe (from 1 to 7 days).

At you can find the schedule of the different metro lines, a map, the prices and also an APP which you can download on your smartphone. Tip: If you already have Google Maps on your smartphone, you can use this also for your route planning with public transports.


The official language in Spain is Spanish (Castilian). But there are different other languages like Catalan (spoken in Catalonia and the Balearic Islands), Galician (in Galicia) and Basque (in the Basque Country and Navarre).

The language of the congress is English.

Currency and Exchange

As Spain is a member of the European Union the currency is the Euro (€), divided into 100 Cent. Currency can be exchanged at the airport, banks and exchange offices. ATMs are widely available.

In Madrid, you may tip or not depending exclusively on how happy you are with the service you get. Among the locals, at least, it’s always been up to the consumer to decide whether and how much to tip.
Some restaurants may add a 2- or 3-euro charge to the bill for bread and appetizers, a service which they have the obligation to tell you about and which you can refuse. Remember that in all establishments, service is included in the price. This isn’t the case in hotels and restaurants, where the legend ‘IVA NO INCLUIDO’ (VAT NOT INCLUDED) usually comes next to the price. This means you should add 10%.


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The electrical supply in Spain is 230 Volts, alternating at 50 cycles per seconds.. Sockets are suitable for euro plugs and plugs of Type F (grounding clips on both sides). If your plug doesn’t fit this descriptions, you may need a plug adapter. If you travel with a device that does not accept 230 Volts at 50 Hertz, you will also need a voltage converter.


The organizers are not liable for damages and/or losses of any kind which may be incurred by the meeting delegates or by any other individuals accompanying them, both during the official activities as well as going to/from the meeting. Delegates are responsible for their own safety and belongings.

Insurance and Vaccinations

The registration fee does not cover insurance for the delegates. The organizers recommend that delegates take out an insurance in their home country to cover prejourney cancellation for personal reasons and to cover accidents, medical expenses and loss of personal belongings during the visit. No vaccinations are needed when visiting Spain.


Passport and Visas

Please check on the website of the Federal Foreign Office which you will find on the following link if you need to apply for a visa to travel to Spain.

It is the sole responsibility of the attendee to take care of his / her visa requirements. Attendees who require an entry visa must allow sufficient time for the application procedure. Attendees should contact the nearest embassy or consulate to determine the appropriate timing of their visa applications. It is recommended to apply for a visa at least 3 months in advance of the Congress. When the registration has already been paid, the registration fee minus a handling fee of 50 EUR will be refunded after the Congress if the visa was applied for in time, and proof of this, together with an official notice from the embassy confirming that a visa could not be granted, is forwarded to: This email address is being protected from spambots. You need JavaScript enabled to view it.

Letter of invitation

If you need a letter of invitation for your visa please contact the congress organizer Pia Schröder at solution office (This email address is being protected from spambots. You need JavaScript enabled to view it.). Please note that a letter of invitation will only be issued after you have registered and paid for the congress.

Sponsors & Exhibitors

There are several opportunities to sponsor the ETS annual meeting. Please have a look at the application form (coming soon) or contact the meeting organisation directly under: This email address is being protected from spambots. You need JavaScript enabled to view it.

Last Updated: 04 August 2020